The 2016 UK Tour of Little Shop of Horrors ran from August 4, 2016 through November 26, 2016.
- Sam Lupton as Seymour Krelborn
- Stephanie Clift as Audrey
- Paul Kissaun as Mr. Mushnik
- Rhydian Roberts as Orin Scrivello, D.D.S.
- Josh Wilmott as Audrey II and Audrey II Puppeteer
- Sasha Latoya as Crystal
- Vanessa Fisher as Chiffon
- Cassie Clare as Ronnette